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Combination of Size-Exclusion Chromatography and Ultracentrifugation Improves the Proteomic Profiling of Plasma-Derived Small Extracellular Vesicles

BACKGROUND: Circulating small extracellular vesicles (sEVs) and its associated proteins are of great interest in the early detection of many diseases. However, there is no gold standard for plasma sEVs isolation, especially for proteomic profiling which could be largely affected by contamination suc...

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Detalles Bibliográficos
Autores principales: Wei, Rui, Zhao, Libo, Kong, Guanyi, Liu, Xiang, Zhu, Shengtao, Zhang, Shutian, Min, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313174/
https://www.ncbi.nlm.nih.gov/pubmed/32587481
http://dx.doi.org/10.1186/s12575-020-00125-5