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Combination of Size-Exclusion Chromatography and Ultracentrifugation Improves the Proteomic Profiling of Plasma-Derived Small Extracellular Vesicles
BACKGROUND: Circulating small extracellular vesicles (sEVs) and its associated proteins are of great interest in the early detection of many diseases. However, there is no gold standard for plasma sEVs isolation, especially for proteomic profiling which could be largely affected by contamination suc...
Autores principales: | Wei, Rui, Zhao, Libo, Kong, Guanyi, Liu, Xiang, Zhu, Shengtao, Zhang, Shutian, Min, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313174/ https://www.ncbi.nlm.nih.gov/pubmed/32587481 http://dx.doi.org/10.1186/s12575-020-00125-5 |
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