β-catenin promotes MTX resistance of leukemia cells by down-regulating FPGS expression via NF-κB

BACKGROUND: Aberrant activation of β-catenin has been shown to play important roles in the chemoresistance of acute lymphoblastic leukemia (ALL), but the involvement and mechanism of β-catenin in methotrexate (MTX) resistance is poorly understood. In the present study, we demonstrate a critical role...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Shu-Guang, Yue, Zhi-Xia, Li, Zhi-Gang, Zhang, Rui-Dong, Zheng, Hu-Yong, Zhao, Xiao-Xi, Gao, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313175/
https://www.ncbi.nlm.nih.gov/pubmed/32587478
http://dx.doi.org/10.1186/s12935-020-01364-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313175/
https://www.ncbi.nlm.nih.gov/pubmed/32587478
http://dx.doi.org/10.1186/s12935-020-01364-y

Ejemplares similares