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β-catenin promotes MTX resistance of leukemia cells by down-regulating FPGS expression via NF-κB

BACKGROUND: Aberrant activation of β-catenin has been shown to play important roles in the chemoresistance of acute lymphoblastic leukemia (ALL), but the involvement and mechanism of β-catenin in methotrexate (MTX) resistance is poorly understood. In the present study, we demonstrate a critical role...

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Detalles Bibliográficos
Autores principales:	Liu, Shu-Guang, Yue, Zhi-Xia, Li, Zhi-Gang, Zhang, Rui-Dong, Zheng, Hu-Yong, Zhao, Xiao-Xi, Gao, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313175/ https://www.ncbi.nlm.nih.gov/pubmed/32587478 http://dx.doi.org/10.1186/s12935-020-01364-y

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