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Heme-Dependent ER Stress Apoptosis: A Mechanism for the Selective Toxicity of the Dihydroartemisinin, NSC735847, in Colorectal Cancer Cells

Colorectal cancer (CRC) is a leading cause of cancer death in the United States. Artemisinin derivatives, including the dihydroartemisinin (DHA) monomers, are widely used as clinical agents for the treatment of malaria. Numerous studies demonstrate that these molecules also display antineoplastic ac...

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Detalles Bibliográficos
Autores principales: Elhassanny, Ahmed E. M., Soliman, Eman, Marie, Mona, McGuire, Paul, Gul, Waseem, ElSohly, Mahmoud, Van Dross, Rukiyah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313430/
https://www.ncbi.nlm.nih.gov/pubmed/32626657
http://dx.doi.org/10.3389/fonc.2020.00965