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Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition

It has been demonstrated from previous studies about the killing effect of dihydroartemisinin (DHA) on glioblastoma, which involves multiple aspects: cytotoxicity, cell cycle arrest and invasion inhibition. DHA has the advantages of low cytotoxicity to normal cells, selective killing effect and low...

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Detalles Bibliográficos
Autores principales: Yi, Renxin, Wang, Handong, Deng, Chulei, Wang, Xinyue, Yao, Lei, Niu, Wenhao, Fei, Maoxing, Zhaba, Wangdui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313443/
https://www.ncbi.nlm.nih.gov/pubmed/32452511
http://dx.doi.org/10.1042/BSR20193314