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Ganoderma lucidum polysaccharide (GLP) enhances antitumor immune response by regulating differentiation and inhibition of MDSCs via a CARD9-NF-κB-IDO pathway

A homogeneous polysaccharide (GLP), with an average molecular weight of 4.44 × 10(4) Da, was isolated and purified from the fruiting bodies of Ganoderma lucidum. In this work, we examined the antitumor activities of GLP using a mouse Lewis lung cancer (LLC) model and explored possible molecular path...

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Detalles Bibliográficos
Autores principales: Wang, Yongyong, Fan, Xiaowu, Wu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313449/
https://www.ncbi.nlm.nih.gov/pubmed/32530032
http://dx.doi.org/10.1042/BSR20201170