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Insights into the Mn(2+) Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals

Agmatine is a neurotransmitter with anticonvulsant, anti-neurotoxic and antidepressant-like effects, in addition it has hypoglycemic actions. Agmatine is converted to putrescine and urea by agmatinase (AGM) and by an agmatinase-like protein (ALP), a new type of enzyme which is present in human and r...

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Detalles Bibliográficos
Autores principales: Reyes, María-Belen, Martínez-Oyanedel, José, Navarrete, Camila, Mardones, Erika, Martínez, Ignacio, Salas, Mónica, López, Vasthi, García-Robles, María, Tarifeño-Saldivia, Estefania, Figueroa, Maximiliano, García, David, Uribe, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313459/
https://www.ncbi.nlm.nih.gov/pubmed/32531922
http://dx.doi.org/10.3390/ijms21114132