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Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses

Viruses and their hosts are locked in an evolutionary race where resistance to infection is acquired by the hosts while viruses develop strategies to circumvent these host defenses. Forming one arm of the host defense armory are cell autonomous restriction factors like Fv1. Originally described as p...

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Detalles Bibliográficos
Autores principales: Yap, Melvyn W., Young, George R., Varnaite, Renata, Morand, Serge, Stoye, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313476/
https://www.ncbi.nlm.nih.gov/pubmed/32525879
http://dx.doi.org/10.1371/journal.pgen.1008471