Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype

OBJECTIVES: Sepsis is a leading cause of death in the United States. Putative targets to prevent systemic inflammatory response syndrome include antagonism of toll-like receptors 2 and 4 and CD44 receptors in vascular endothelial cells. Proteoglycan-4 is a mucinous glycoprotein that interacts with C...

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Detalles Bibliográficos
Autores principales: Richendrfer, Holly A., Levy, Mitchell M., Elsaid, Khaled A., Schmidt, Tannin A., Zhang, Ling, Cabezas, Ralph, Jay, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Original Basic Science Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314356/
https://www.ncbi.nlm.nih.gov/pubmed/32695993
http://dx.doi.org/10.1097/CCE.0000000000000126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314356/
https://www.ncbi.nlm.nih.gov/pubmed/32695993
http://dx.doi.org/10.1097/CCE.0000000000000126

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