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Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium

Using serial analysis of myocardial gene expression employing endomyocardial biopsy starting material in a dilated cardiomyopathy cohort, we show that mRNA expression of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) cardiac myocyte receptor ACE2 is up-regulated with remodeling and...

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Detalles Bibliográficos
Autores principales: Bristow, Michael R., Zisman, Lawrence S., Altman, Natasha L., Gilbert, Edward M., Lowes, Brian D., Minobe, Wayne A., Slavov, Dobromir, Schwisow, Jessica A., Rodriguez, Erin M., Carroll, Ian A., Keuer, Thomas A., Buttrick, Peter M., Kao, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314447/
https://www.ncbi.nlm.nih.gov/pubmed/32838074
http://dx.doi.org/10.1016/j.jacbts.2020.06.007