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Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family

Set1A and Set1B, two members of the COMPASS family of methyltransferases that methylate the histone H3 lysine 4 (H3K4) residue, have been accredited as primary depositors of global H3K4 trimethylation (H3K4me3) in mammalian cells. Our previous studies in mouse embryonic stem cells (ESCs) demonstrate...

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Detalles Bibliográficos
Autores principales: Sze, Christie C., Ozark, Patrick A., Cao, Kaixiang, Ugarenko, Michal, Das, Siddhartha, Wang, Lu, Marshall, Stacy A., Rendleman, Emily J., Ryan, Caila A., Zha, Didi, Douillet, Delphine, Chen, Fei Xavier, Shilatifard, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314515/
https://www.ncbi.nlm.nih.gov/pubmed/32637595
http://dx.doi.org/10.1126/sciadv.aaz4764