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Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Q(pool)

Mitochondrial respiratory complexes assemble into supercomplexes (SC). Q-respirasome (III(2) + IV) requires the supercomplex assembly factor (SCAF1) protein. The role of this factor in the N-respirasome (I + III(2) + IV) and the physiological role of SCs are controversial. Here, we study C57BL/6J mi...

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Detalles Bibliográficos
Autores principales: Calvo, Enrique, Cogliati, Sara, Hernansanz-Agustín, Pablo, Loureiro-López, Marta, Guarás, Adela, Casuso, Rafael A., García-Marqués, Fernando, Acín-Pérez, Rebeca, Martí-Mateos, Yolanda, Silla-Castro, JC., Carro-Alvarellos, Marta, Huertas, Jesús R., Vázquez, Jesús, Enríquez, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314541/
https://www.ncbi.nlm.nih.gov/pubmed/32637615
http://dx.doi.org/10.1126/sciadv.aba7509