Nuclei determine the spatial origin of mitotic waves

Traveling waves play an essential role in coordinating mitosis over large distances, but what determines the spatial origin of mitotic waves remains unclear. Here, we show that such waves initiate at pacemakers, regions that oscillate faster than their surroundings. In cell-free extracts of Xenopus...

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Detalles Bibliográficos
Autores principales: Nolet, Felix E, Vandervelde, Alexandra, Vanderbeke, Arno, Piñeros, Liliana, Chang, Jeremy B, Gelens, Lendert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314552/
https://www.ncbi.nlm.nih.gov/pubmed/32452767
http://dx.doi.org/10.7554/eLife.52868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314552/
https://www.ncbi.nlm.nih.gov/pubmed/32452767
http://dx.doi.org/10.7554/eLife.52868

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