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Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate

Self-renewal and differentiation of hematopoietic stem cells (HSCs) are orchestrated by the combinatorial action of transcription factors and epigenetic regulators. Here, we have explored the mechanism by which histone H4 lysine 16 acetyltransferase MOF regulates erythropoiesis. Single-cell RNA sequ...

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Detalles Bibliográficos
Autores principales: Pessoa Rodrigues, Cecilia, Herman, Josip Stefan, Herquel, Benjamin, Valsecchi, Claudia Isabelle Keller, Stehle, Thomas, Grün, Dominic, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314555/
https://www.ncbi.nlm.nih.gov/pubmed/32671208
http://dx.doi.org/10.1126/sciadv.aaz4815