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Structural and Functional Insight Into the Glycosylation Impact Upon the HGF/c-Met Signaling Pathway

Upon interactions with its specific ligand hepatocyte growth factor (HGF), the c-Met signal is relayed to series of downstream pathways, exerting essential biological roles. Dysregulation of the HGF-c-Met signaling pathway has been implicated in the onset, progression and metastasis of various cance...

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Detalles Bibliográficos
Autores principales: Hu, Xinyue, Tang, Feiyu, Liu, Peilin, Zhong, Taowei, Yuan, Fengyan, He, Quanyuan, von Itzstein, Mark, Li, Hao, Weng, Liang, Yu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314907/
https://www.ncbi.nlm.nih.gov/pubmed/32626713
http://dx.doi.org/10.3389/fcell.2020.00490