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Structural and Functional Insight Into the Glycosylation Impact Upon the HGF/c-Met Signaling Pathway
Upon interactions with its specific ligand hepatocyte growth factor (HGF), the c-Met signal is relayed to series of downstream pathways, exerting essential biological roles. Dysregulation of the HGF-c-Met signaling pathway has been implicated in the onset, progression and metastasis of various cance...
Autores principales: | Hu, Xinyue, Tang, Feiyu, Liu, Peilin, Zhong, Taowei, Yuan, Fengyan, He, Quanyuan, von Itzstein, Mark, Li, Hao, Weng, Liang, Yu, Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314907/ https://www.ncbi.nlm.nih.gov/pubmed/32626713 http://dx.doi.org/10.3389/fcell.2020.00490 |
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