Prediabetes Induced by a Single Autoimmune B Cell Clone

While B cells play a significant role in the onset of type-1 diabetes (T1D), little is know about their role in those early stages. Thus, to gain new insights into the role of B cells in T1D, we converted a physiological early pancreas-infiltrating B cell into a novel BCR mouse model using Somatic C...

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Detalles Bibliográficos
Autores principales: Phillips, Nathaniel, Ke, Eugene, Nham, Amy, Seidl, Maximilian, Freeman, Brent, Abadejos, Justin R., Xiao, Changchun, Nemazee, David, Ku, Manching, Kirak, Oktay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314986/
https://www.ncbi.nlm.nih.gov/pubmed/32625203
http://dx.doi.org/10.3389/fimmu.2020.01073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314986/
https://www.ncbi.nlm.nih.gov/pubmed/32625203
http://dx.doi.org/10.3389/fimmu.2020.01073

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