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Prediabetes Induced by a Single Autoimmune B Cell Clone
While B cells play a significant role in the onset of type-1 diabetes (T1D), little is know about their role in those early stages. Thus, to gain new insights into the role of B cells in T1D, we converted a physiological early pancreas-infiltrating B cell into a novel BCR mouse model using Somatic C...
Autores principales: | Phillips, Nathaniel, Ke, Eugene, Nham, Amy, Seidl, Maximilian, Freeman, Brent, Abadejos, Justin R., Xiao, Changchun, Nemazee, David, Ku, Manching, Kirak, Oktay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314986/ https://www.ncbi.nlm.nih.gov/pubmed/32625203 http://dx.doi.org/10.3389/fimmu.2020.01073 |
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