Cargando…
The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages
A host of chronic inflammatory diseases are accelerated by the formation of the powerful oxidant hypochlorous acid (HOCl) by myeloperoxidase (MPO). In the presence of thiocyanate (SCN(-)), the production of HOCl by MPO is decreased in favour of the formation of a milder oxidant, hypothiocyanous acid...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315103/ https://www.ncbi.nlm.nih.gov/pubmed/32570189 http://dx.doi.org/10.1016/j.redox.2020.101602 |