Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition

It is well understood that the adaptive immune response to infectious agents includes a modulating suppressive component as well as an activating component. We now show that the very early innate response also has an immunosuppressive component. Infected cells upregulate the CD47 “don’t eat me” sign...

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Detalles Bibliográficos
Autores principales: Tal, Michal Caspi, Torrez Dulgeroff, Laughing Bear, Myers, Lara, Cham, Lamin B., Mayer-Barber, Katrin D., Bohrer, Andrea C., Castro, Ehydel, Yiu, Ying Ying, Lopez Angel, Cesar, Pham, Ed, Carmody, Aaron B., Messer, Ronald J., Gars, Eric, Kortmann, Jens, Markovic, Maxim, Hasenkrug, Michaela, Peterson, Karin E., Winkler, Clayton W., Woods, Tyson A., Hansen, Paige, Galloway, Sarah, Wagh, Dhananjay, Fram, Benjamin J., Nguyen, Thai, Corey, Daniel, Kalluru, Raja Sab, Banaei, Niaz, Rajadas, Jayakumar, Monack, Denise M., Ahmed, Aijaz, Sahoo, Debashis, Davis, Mark M., Glenn, Jeffrey S., Adomati, Tom, Lang, Karl S., Weissman, Irving L., Hasenkrug, Kim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315125/
https://www.ncbi.nlm.nih.gov/pubmed/32576678
http://dx.doi.org/10.1128/mBio.01293-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315125/
https://www.ncbi.nlm.nih.gov/pubmed/32576678
http://dx.doi.org/10.1128/mBio.01293-20

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