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Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress

The presence of glioma stem cells (GSCs), which are enriched in neurospheres, may be connected to the radioresistance of glioblastoma (GBM) due to their enhanced antioxidant defense and elevated DNA repair capacity. The aim was to evaluate the responses to different radiation qualities and to reduce...

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Detalles Bibliográficos
Autores principales: Godoy, Paulo R. D. V., Pour Khavari, Ali, Rizzo, Marzia, Sakamoto-Hojo, Elza T., Haghdoost, Siamak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315280/
https://www.ncbi.nlm.nih.gov/pubmed/32617133
http://dx.doi.org/10.1155/2020/2534643