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Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

Burkholderia cenocepacia is an opportunistic bacterial pathogen that causes severe pulmonary infections in cystic fibrosis and chronic granulomatous disease patients. B. cenocepacia can survive inside infected macrophages within the B. cenocepacia-containing vacuole (BcCV) and to elicit a severe inf...

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Detalles Bibliográficos
Autores principales: Walpole, Glenn F.W., Plumb, Jonathan D., Chung, Daniel, Tang, Brandon, Boulay, Benoit, Osborne, Douglas G., Piotrowski, Joshua T., Catz, Sergio D., Billadeau, Daniel D., Grinstein, Sergio, Jaumouillé, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315377/
https://www.ncbi.nlm.nih.gov/pubmed/32492429
http://dx.doi.org/10.1016/j.celrep.2020.107721