Boosting the Synthesis of Pharmaceutically Active Abietane Diterpenes in S. sclarea Hairy Roots by Engineering the GGPPS and CPPS Genes

Abietane diterpenoids (ADs), synthesized in the roots of different Salvia species, such as aethiopinone, 1-oxoaethiopinone, salvipisone, and ferruginol, have a variety of known biological activities. We have shown that aethiopinone has promising cytotoxic activity against several human tumor cell li...

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Detalles Bibliográficos
Autores principales: Vaccaro, Maria Carmela, Alfieri, Mariaevelina, De Tommasi, Nunziatina, Moses, Tessa, Goossens, Alain, Leone, Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315395/
https://www.ncbi.nlm.nih.gov/pubmed/32625231
http://dx.doi.org/10.3389/fpls.2020.00924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315395/
https://www.ncbi.nlm.nih.gov/pubmed/32625231
http://dx.doi.org/10.3389/fpls.2020.00924

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