cfNOMe — A single assay for comprehensive epigenetic analyses of cell-free DNA

Cell-free DNA (cfDNA) analysis has become essential in cancer diagnostics and prenatal testing. We present cfNOMe, a two-in-one method of measuring cfDNA cytosine methylation and nucleosome occupancy in a single assay using non-disruptive enzymatic cytosine conversion and a custom bioinformatic pipe...

Descripción completa

Detalles Bibliográficos
Autores principales: Erger, Florian, Nörling, Deborah, Borchert, Domenica, Leenen, Esther, Habbig, Sandra, Wiesener, Michael S., Bartram, Malte P., Wenzel, Andrea, Becker, Christian, Toliat, Mohammad R., Nürnberg, Peter, Beck, Bodo B., Altmüller, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315486/
https://www.ncbi.nlm.nih.gov/pubmed/32580754
http://dx.doi.org/10.1186/s13073-020-00750-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315486/
https://www.ncbi.nlm.nih.gov/pubmed/32580754
http://dx.doi.org/10.1186/s13073-020-00750-5

Ejemplares similares