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cfNOMe — A single assay for comprehensive epigenetic analyses of cell-free DNA
Cell-free DNA (cfDNA) analysis has become essential in cancer diagnostics and prenatal testing. We present cfNOMe, a two-in-one method of measuring cfDNA cytosine methylation and nucleosome occupancy in a single assay using non-disruptive enzymatic cytosine conversion and a custom bioinformatic pipe...
Autores principales: | Erger, Florian, Nörling, Deborah, Borchert, Domenica, Leenen, Esther, Habbig, Sandra, Wiesener, Michael S., Bartram, Malte P., Wenzel, Andrea, Becker, Christian, Toliat, Mohammad R., Nürnberg, Peter, Beck, Bodo B., Altmüller, Janine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315486/ https://www.ncbi.nlm.nih.gov/pubmed/32580754 http://dx.doi.org/10.1186/s13073-020-00750-5 |
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