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NLRP3 inflammasome inhibitor MCC950 attenuates primary dysmenorrhea in mice via the NF-κB/COX-2/PG pathway

BACKGROUND: Primary dysmenorrhea (PD) constitutes a common gynecological disease among young women. The NLRP3 inflammasome may be activated and expressed in PD, but the mechanistic link between NLRP3 inflammasome activation and PD is still unclear. METHODS: To investigate the potential role of NLRP3...

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Detalles Bibliográficos
Autores principales: Tang, Biao, Liu, Dan, Chen, Lingyu, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315492/
https://www.ncbi.nlm.nih.gov/pubmed/32595419
http://dx.doi.org/10.1186/s12950-020-00251-7