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NLRP3 inflammasome inhibitor MCC950 attenuates primary dysmenorrhea in mice via the NF-κB/COX-2/PG pathway
BACKGROUND: Primary dysmenorrhea (PD) constitutes a common gynecological disease among young women. The NLRP3 inflammasome may be activated and expressed in PD, but the mechanistic link between NLRP3 inflammasome activation and PD is still unclear. METHODS: To investigate the potential role of NLRP3...
Autores principales: | Tang, Biao, Liu, Dan, Chen, Lingyu, Liu, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315492/ https://www.ncbi.nlm.nih.gov/pubmed/32595419 http://dx.doi.org/10.1186/s12950-020-00251-7 |
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