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Including non-concurrent control patients in the analysis of platform trials: is it worth it?
BACKGROUND: Platform trials allow adding new experimental treatments to an on-going trial. This feature is attractive to practitioners due to improved efficiency. Nevertheless, the operating characteristics of a trial that adds arms have not been well-studied. One controversy is whether just the con...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315495/ https://www.ncbi.nlm.nih.gov/pubmed/32580702 http://dx.doi.org/10.1186/s12874-020-01043-6 |