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Including non-concurrent control patients in the analysis of platform trials: is it worth it?

BACKGROUND: Platform trials allow adding new experimental treatments to an on-going trial. This feature is attractive to practitioners due to improved efficiency. Nevertheless, the operating characteristics of a trial that adds arms have not been well-studied. One controversy is whether just the con...

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Detalles Bibliográficos
Autores principales: Lee, Kim May, Wason, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315495/
https://www.ncbi.nlm.nih.gov/pubmed/32580702
http://dx.doi.org/10.1186/s12874-020-01043-6