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LncRNA FTX represses the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via regulating the M1/M2 polarization of Kupffer cells

BACKGROUND: The effect of lncRNA FTX on non-alcoholic fatty liver disease (NAFLD) conversion to hepatocellular carcinoma (HCC) is unclear. METHODS: In our study, C57BL/6 mice was fed with high fat diet for obtaining NAFLD mouse model, and diethylnitrosamine induced the formation of HCC tumor. The ex...

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Detalles Bibliográficos
Autores principales: Wu, Huajun, Zhong, Zhiwei, Wang, Anji, Yuan, Chunhui, Ning, Ke, Hu, Huanhuan, Wang, Chao, Yin, Xiangbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315496/
https://www.ncbi.nlm.nih.gov/pubmed/32595415
http://dx.doi.org/10.1186/s12935-020-01354-0