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Bmi-1-induced miR-27a and miR-155 promote tumor metastasis and chemoresistance by targeting RKIP in gastric cancer

BACKGROUND: We previously reported an inverse relationship between B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP), which is associated with the prognosis of gastric cancer (GC). In this study, we further explored the microRNA (miRNA)...

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Detalles Bibliográficos
Autores principales: Li, Yaqing, Tian, Zhenfeng, Tan, Ying, Lian, Guoda, Chen, Shangxiang, Chen, Shaojie, Li, Jiajia, Li, Xuanna, Huang, Kaihong, Chen, Yinting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315508/
https://www.ncbi.nlm.nih.gov/pubmed/32580736
http://dx.doi.org/10.1186/s12943-020-01229-y