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Single-cell transcriptome and antigen-immunoglobin analysis reveals the diversity of B cells in non-small cell lung cancer

BACKGROUND: Malignant transformation and progression of cancer are driven by the co-evolution of cancer cells and their dysregulated tumor microenvironment (TME). Recent studies on immunotherapy demonstrate the efficacy in reverting the anti-tumoral function of T cells, highlighting the therapeutic...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Tan, Yun, Sun, Fenghuan, Hou, Likun, Zhang, Chi, Ge, Tao, Yu, Huansha, Wu, Chunxiao, Zhu, Yuming, Duan, Liang, Wu, Liang, Song, Nan, Zhang, Liping, Zhang, Wei, Wang, Di, Chen, Chang, Wu, Chunyan, Jiang, Gening, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315523/
https://www.ncbi.nlm.nih.gov/pubmed/32580738
http://dx.doi.org/10.1186/s13059-020-02064-6