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A comparison of epigenetic mitotic-like clocks for cancer risk prediction

BACKGROUND: DNA methylation changes that accrue in the stem cell pool of an adult tissue in line with the cumulative number of cell divisions may contribute to the observed variation in cancer risk among tissues and individuals. Thus, the construction of epigenetic “mitotic” clocks that can measure...

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Detalles Bibliográficos
Autor principal: Teschendorff, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315560/
https://www.ncbi.nlm.nih.gov/pubmed/32580750
http://dx.doi.org/10.1186/s13073-020-00752-3