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A comparison of epigenetic mitotic-like clocks for cancer risk prediction
BACKGROUND: DNA methylation changes that accrue in the stem cell pool of an adult tissue in line with the cumulative number of cell divisions may contribute to the observed variation in cancer risk among tissues and individuals. Thus, the construction of epigenetic “mitotic” clocks that can measure...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315560/ https://www.ncbi.nlm.nih.gov/pubmed/32580750 http://dx.doi.org/10.1186/s13073-020-00752-3 |