Sofosbuvir Thio-analogues: Synthesis and Antiviral Evaluation of the First Novel Pyridine- and Pyrimidine-Based Thioglycoside Phosphoramidates

[Image: see text] The synthesis and antiviral screening of the first reported series of pyridine- and pyrimidine-based thioglycoside phosphoramidates are herein reported. They were prepared through two synthetic steps: The first step is via coupling of mercapto-derivatized heterocyclic bases with th...

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Detalles Bibliográficos
Autores principales: Abu-Zaied, Mamdouh Attia, Hammad, Sherif F., Halaweish, Fathi T., Elgemeie, Galal Hamza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315579/
https://www.ncbi.nlm.nih.gov/pubmed/32596602
http://dx.doi.org/10.1021/acsomega.0c01364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315579/
https://www.ncbi.nlm.nih.gov/pubmed/32596602
http://dx.doi.org/10.1021/acsomega.0c01364

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