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Recognition and Unfolding of c-MYC and Telomeric G-Quadruplex DNAs by the RecQ C-Terminal Domain of Human Bloom Syndrome Helicase

[Image: see text] G-quadruplex (G4) is a noncanonical DNA secondary structure formed by Hoogsteen base pairing. It is recognized by various DNA helicases involved in DNA metabolism processes such as replication and transcription. Human Bloom syndrome protein (BLM), one of five human RecQ helicases,...

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Detalles Bibliográficos
Autores principales: Lee, Sungjin, Kim, Jinwoo, Han, Suyeong, Park, Chin-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315595/
https://www.ncbi.nlm.nih.gov/pubmed/32596589
http://dx.doi.org/10.1021/acsomega.0c01176