Integrin alpha-5 silencing leads to myofibroblastic differentiation in IPF-derived human lung fibroblasts

BACKGROUND AND OBJECTIVE: The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerated amounts of extracellular matrix proteins and modifyi...

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Detalles Bibliográficos
Autores principales: Shochet, Gali Epstein, Brook, Elizabetha, Bardenstein-Wald, Becky, Grobe, Hanna, Edelstein, Evgeny, Israeli-Shani, Lilach, Shitrit, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315658/
https://www.ncbi.nlm.nih.gov/pubmed/32637060
http://dx.doi.org/10.1177/2040622320936023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315658/
https://www.ncbi.nlm.nih.gov/pubmed/32637060
http://dx.doi.org/10.1177/2040622320936023

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