Colorectal cancer cells promote osteoclastogenesis and bone destruction through regulating EGF/ERK/CCL3 pathway

Bone metastasis of colorectal cancer (CRC) cells leads to osteolysis. Aberrant activation of osteoclasts is responsible for bone resorption in tumor. In general, bone marrow-derived monocytes (BMMs) differentiate into osteoclasts, however, how CRC cells interact with BMMs and how to regulate the dif...

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Detalles Bibliográficos
Autores principales: Zi-chen, Gong, Jin, Qian, Yi-na, Zhang, Wei, Wang, Xia, Kang, Wei, Xu, Juan, Wu, Wei, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315727/
https://www.ncbi.nlm.nih.gov/pubmed/32478376
http://dx.doi.org/10.1042/BSR20201175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315727/
https://www.ncbi.nlm.nih.gov/pubmed/32478376
http://dx.doi.org/10.1042/BSR20201175

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