Cargando…

Colorectal cancer cells promote osteoclastogenesis and bone destruction through regulating EGF/ERK/CCL3 pathway

Bone metastasis of colorectal cancer (CRC) cells leads to osteolysis. Aberrant activation of osteoclasts is responsible for bone resorption in tumor. In general, bone marrow-derived monocytes (BMMs) differentiate into osteoclasts, however, how CRC cells interact with BMMs and how to regulate the dif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zi-chen, Gong, Jin, Qian, Yi-na, Zhang, Wei, Wang, Xia, Kang, Wei, Xu, Juan, Wu, Wei, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315727/ https://www.ncbi.nlm.nih.gov/pubmed/32478376 http://dx.doi.org/10.1042/BSR20201175

Ejemplares similares

Interleukin‐37 inhibits osteoclastogenesis and alleviates inflammatory bone destruction
por: Tang, Ruohui, et al.
Publicado: (2018)

Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF-κB pathways and promotes osteoclastogenesis in human oral cancer cells
por: Tang, Chih-Hsin, et al.
Publicado: (2008)

The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction
por: Shimo, Tsuyoshi, et al.
Publicado: (2016)

Revisiting CCL-type chemokines in breast cancer and its milieu: prominent targetable chemokines, CCL8 and CCL21
por: Unver, Nese
Publicado: (2021)

Implication of the Association of Fibrinogen Citrullination and Osteoclastogenesis in Bone Destruction in Rheumatoid Arthritis
por: Kim, Ji Soo, et al.
Publicado: (2020)

Interactions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis
por: Wang, Haicheng, et al.
Publicado: (2023)

Tetrandrine enhances the ubiquitination and degradation of Syk through an AhR-c-src-c-Cbl pathway and consequently inhibits osteoclastogenesis and bone destruction in arthritis
por: Jia, Yugai, et al.
Publicado: (2019)

LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway
por: Zhang, Quan, et al.
Publicado: (2020)

The overexpression of AUF1 in colorectal cancer predicts a poor prognosis and promotes cancer progression by activating ERK and AKT pathways
por: Tian, Xin‐Yuan, et al.
Publicado: (2020)

Alendronate‐anchored PEGylation of ceria nanoparticles promotes human hepatoma cell proliferation via AKT/ERK signaling pathways
por: Cheng, Heng, et al.
Publicado: (2017)

GPR84 potently inhibits osteoclastogenesis and alleviates osteolysis in bone metastasis of colorectal cancer
por: Jian, Li, et al.
Publicado: (2023)

ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1
por: Balmanno, Kathryn, et al.
Publicado: (2023)

Structural basis of the effect of activating mutations on the EGF receptor
por: Galdadas, Ioannis, et al.
Publicado: (2021)

C-C Motif Chemokine Ligand 5 (CCL5) Promotes Irradiation-Evoked Osteoclastogenesis
por: Wang, Jing, et al.
Publicado: (2023)

Lactic acid promotes metastatic niche formation in bone metastasis of colorectal cancer
por: Qian, Jin, et al.
Publicado: (2021)

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
por: Walens, Andrea, et al.
Publicado: (2019)

Dendritic cells-derived interferon-λ1 ameliorated inflammatory bone destruction through inhibiting osteoclastogenesis
por: Chen, Yueqi, et al.
Publicado: (2020)

PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma
por: Jiang, Hai, et al.
Publicado: (2018)

CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis
por: Lee, Dabin, et al.
Publicado: (2018)

RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1
por: Wang, Tao, et al.
Publicado: (2019)

miR-492 promotes chemoresistance to CDDP and metastasis by targeting inhibiting DNMT3B and induces stemness in gastric cancer
por: Wu, Shuai, et al.
Publicado: (2020)

DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells
por: Sung, Nam Ji, et al.
Publicado: (2020)

lncRNA-u50535 promotes the progression of lung cancer by activating CCL20/ERK signaling
por: Wei, Wei, et al.
Publicado: (2019)

Rap1A promotes ovarian cancer metastasis via activation of ERK/p38 and notch signaling
por: Lu, Lili, et al.
Publicado: (2016)

Loss of RUNX3 expression promotes cancer‐associated bone destruction by regulating CCL5, CCL19 and CXCL11 in non‐small cell lung cancer
por: Kim, Hyun‐Jeong, et al.
Publicado: (2015)

Lonafarnib Inhibits Farnesyltransferase via Suppressing ERK Signaling Pathway to Prevent Osteoclastogenesis in Titanium Particle-Induced Osteolysis
por: Huang, Linke, et al.
Publicado: (2022)

Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
por: Lin, Neng-Yu, et al.
Publicado: (2023)

Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma
por: Miyata, Kohei, et al.
Publicado: (2014)

Curcumin inhibits the migration of osteoclast precursors and osteoclastogenesis by repressing CCL3 production
por: Liang, Zhengeng, et al.
Publicado: (2020)

The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer
por: Wang, Dingzhi, et al.
Publicado: (2011)

Long non-coding RNA ROR1-AS1 induces tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway
por: Wang, Wei, et al.
Publicado: (2019)

Casticin suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating the AKT/ERK and NF-κB signaling pathways
por: Yang, Fan, et al.
Publicado: (2023)

CCL2/EGF positive feedback loop between cancer cells and macrophages promotes cell migration and invasion in head and neck squamous cell carcinoma
por: Gao, Lu, et al.
Publicado: (2016)

Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma
por: Shigeoka, Manabu, et al.
Publicado: (2015)

USP14 as a novel prognostic marker promotes cisplatin resistance via Akt/ERK signaling pathways in gastric cancer
por: Fu, Ying, et al.
Publicado: (2018)

Regulation of Osteoclastogenesis and Bone Resorption by miRNAs
por: Inoue, Kazuki, et al.
Publicado: (2021)

Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway
por: Sheng, Weiwei, et al.
Publicado: (2017)

Akermanite bioceramics promote osteogenesis, angiogenesis and suppress osteoclastogenesis for osteoporotic bone regeneration
por: Xia, Lunguo, et al.
Publicado: (2016)

ERK5 signalling pathway is a novel target of sorafenib: Implication in EGF biology
por: Ortega‐Muelas, Marta, et al.
Publicado: (2021)

MicroRNA‐92a promotes tumor growth and suppresses immune function through activation of MAPK/ERK signaling pathway by inhibiting PTEN in mice bearing U14 cervical cancer
por: Li, Zeng‐Hui, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3jspi1ec2mrg2rvagemjasb3a7