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Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment
[Image: see text] While remdesivir has garnered much hope for its moderate anti-Covid-19 effects, its parent nucleoside, GS-441524, has been overlooked. Pharmacokinetic analysis of remdesivir evidences premature serum hydrolysis to GS-441524; GS-441524 is the predominant metabolite reaching the lung...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315846/ https://www.ncbi.nlm.nih.gov/pubmed/32665809 http://dx.doi.org/10.1021/acsmedchemlett.0c00316 |