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The protean prion protein
The prion protein, PrP, can adopt at least 2 conformations, the overwhelmingly prevalent cellular conformation (PrP(C)) and the scrapie conformation (PrP(Sc)). PrP(C) features a globular C-terminal domain containing 3 α-helices and a short β-sheet and a long flexible N-terminal tail whose exact conf...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316225/ https://www.ncbi.nlm.nih.gov/pubmed/32584805 http://dx.doi.org/10.1371/journal.pbio.3000754 |