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Implications of localized charge for human influenza A H1N1 hemagglutinin evolution: Insights from deep mutational scans
Seasonal influenza A viruses of humans evolve rapidly due to strong selection pressures from host immune responses, principally on the hemagglutinin (HA) viral surface protein. Based on mouse transmission experiments, a proposed mechanism for immune evasion consists of increased avidity to host cell...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316228/ https://www.ncbi.nlm.nih.gov/pubmed/32584807 http://dx.doi.org/10.1371/journal.pcbi.1007892 |