A novel selective PPARα modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanisms

OBJECTIVE: Cardiovascular disease is a leading cause of death worldwide. Obesity-related metabolic disorders including dyslipidemia cause impaired collateralization under ischemic conditions, thereby resulting in exacerbated cardiovascular dysfunction. Pemafibrate is a novel selective PPARα modulato...

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Detalles Bibliográficos
Autores principales: Kawanishi, Hiroshi, Ohashi, Koji, Ogawa, Hayato, Otaka, Naoya, Takikawa, Tomonobu, Fang, Lixin, Ozaki, Yuta, Takefuji, Mikito, Murohara, Toyoaki, Ouchi, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316279/
https://www.ncbi.nlm.nih.gov/pubmed/32584895
http://dx.doi.org/10.1371/journal.pone.0235362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316279/
https://www.ncbi.nlm.nih.gov/pubmed/32584895
http://dx.doi.org/10.1371/journal.pone.0235362

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