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A novel selective PPARα modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanisms

OBJECTIVE: Cardiovascular disease is a leading cause of death worldwide. Obesity-related metabolic disorders including dyslipidemia cause impaired collateralization under ischemic conditions, thereby resulting in exacerbated cardiovascular dysfunction. Pemafibrate is a novel selective PPARα modulato...

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Detalles Bibliográficos
Autores principales:	Kawanishi, Hiroshi, Ohashi, Koji, Ogawa, Hayato, Otaka, Naoya, Takikawa, Tomonobu, Fang, Lixin, Ozaki, Yuta, Takefuji, Mikito, Murohara, Toyoaki, Ouchi, Noriyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316279/ https://www.ncbi.nlm.nih.gov/pubmed/32584895 http://dx.doi.org/10.1371/journal.pone.0235362

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