Secretion of Recombinant Interleukin-22 by Engineered Lactobacillus reuteri Reduces Fatty Liver Disease in a Mouse Model of Diet-Induced Obesity

The incidence of metabolic syndrome continues to rise globally. In mice, intravenous administration of interleukin-22 (IL-22) ameliorates various disease phenotypes associated with diet-induced metabolic syndrome. In patients, oral treatment is favored over intravenous treatment, but methodologies t...

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Detalles Bibliográficos
Autores principales: Oh, Jee-Hwan, Schueler, Kathryn L., Stapleton, Donnie S., Alexander, Laura M., Yen, Chi-Liang Eric, Keller, Mark P., Attie, Alan D., van Pijkeren, Jan-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316485/
https://www.ncbi.nlm.nih.gov/pubmed/32581074
http://dx.doi.org/10.1128/mSphere.00183-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316485/
https://www.ncbi.nlm.nih.gov/pubmed/32581074
http://dx.doi.org/10.1128/mSphere.00183-20

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