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Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner

Loop extrusion by structural maintenance of chromosomes (SMC) complexes has been proposed as a mechanism to organize chromatin in interphase and metaphase. However, the requirements for chromatin organization in these cell cycle phases are different, and it is unknown whether loop extrusion dynamics...

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Detalles Bibliográficos
Autores principales: Golfier, Stefan, Quail, Thomas, Kimura, Hiroshi, Brugués, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316503/
https://www.ncbi.nlm.nih.gov/pubmed/32396063
http://dx.doi.org/10.7554/eLife.53885