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Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner
Loop extrusion by structural maintenance of chromosomes (SMC) complexes has been proposed as a mechanism to organize chromatin in interphase and metaphase. However, the requirements for chromatin organization in these cell cycle phases are different, and it is unknown whether loop extrusion dynamics...
Autores principales: | Golfier, Stefan, Quail, Thomas, Kimura, Hiroshi, Brugués, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316503/ https://www.ncbi.nlm.nih.gov/pubmed/32396063 http://dx.doi.org/10.7554/eLife.53885 |
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