Leptin increases sympathetic nerve activity via induction of its own receptor in the paraventricular nucleus

Whether leptin acts in the paraventricular nucleus (PVN) to increase sympathetic nerve activity (SNA) is unclear, since PVN leptin receptors (LepR) are sparse. We show in rats that PVN leptin slowly increases SNA to muscle and brown adipose tissue, because it induces the expression of its own recept...

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Detalles Bibliográficos
Autores principales: Shi, Zhigang, Pelletier, Nicole E, Wong, Jennifer, Li, Baoxin, Sdrulla, Andrei D, Madden, Christopher J, Marks, Daniel L, Brooks, Virginia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316512/
https://www.ncbi.nlm.nih.gov/pubmed/32538782
http://dx.doi.org/10.7554/eLife.55357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316512/
https://www.ncbi.nlm.nih.gov/pubmed/32538782
http://dx.doi.org/10.7554/eLife.55357

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