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LPS-induced expression and release of monocyte tissue factor in patients with haemophilia

In haemophilia, thrombin generation and fibrin deposition upon vascular injury critically depend on the tissue factor (TF)-driven coagulation pathway. TF expression by monocytes/macrophages and circulating microvesicles contributes to haemostasis, thrombosis and inflammation. Inflammation is a hallm...

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Detalles Bibliográficos
Autores principales: Holstein, Katharina, Matysiak, Anna, Witt, Leonora, Sievers, Bianca, Beckmann, Lennart, Haddad, Munif, Renné, Thomas, Voigtlaender, Minna, Langer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316670/
https://www.ncbi.nlm.nih.gov/pubmed/32430703
http://dx.doi.org/10.1007/s00277-020-04075-6