Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

Ischemia reperfusion (IR) injury may be attenuated through succinate dehydrogenase (SDH) inhibition by dimethyl malonate (DiMAL). Whether SDH inhibition yields protection in diabetic individuals and translates into human cardiac tissue remain unknown. In isolated perfused hearts from 24 weeks old ma...

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Detalles Bibliográficos
Autores principales: Jespersen, Nichlas Riise, Hjortbak, Marie Vognstoft, Lassen, Thomas Ravn, Støttrup, Nicolaj Brejnholt, Johnsen, Jacob, Tonnesen, Pernille Tilma, Larsen, Steen, Kimose, Hans-Henrik, Bøtker, Hans Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316713/
https://www.ncbi.nlm.nih.gov/pubmed/32587298
http://dx.doi.org/10.1038/s41598-020-67247-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316713/
https://www.ncbi.nlm.nih.gov/pubmed/32587298
http://dx.doi.org/10.1038/s41598-020-67247-4

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